Volume 25, Issue 2 (2025)
EFFECTS OF QUR’AN RECITATION ON LEFT VENTRICULAR OUTFLOW TRACT VELOCITY TIME INTEGRAL IN PATIENTS WITH HEART FAILURE WITH REDUCED EJECTION FRACTION
Affiliation Details
  • dr. Nurkhalis, Sp.JP-FIHA,FAsCC: Universitas Syiah Kuala, Banda Aceh
  • Prof. Dr. dr. H. Kurnia Fitri Jamil, M.Kes, Sp.PD-KPTI, FINASIM: University of Syiah Kuala
  • Dr.dr. Imran SpS(K), M.Kes: Universitas Syiah Kuala
  • Dr.dr. Muhammad Yamin, SpJP(K), SpPD: Universitas Indonesia

Abstract

Left ventricular outflow tract velocity time integral (LVOT-VTI) is a noninvasive echocardiographic parameter representing stroke volume. Qur’an recitation has been reported to influence cardiovascular indicators such as heart rate variability and blood pressure, which are indirectly related to cardiac function, although its effect on direct echocardiographic parameters remains unclear. This study aimed to evaluate whether patients with heart failure with reduced ejection fraction (HFrEF) show improvement in cardiac function, as reflected by changes in LVOT-VTI, following Qur’an recitation. A case-control study was conducted involving 30 HFrEF patients divided into three groups: Group 1 recited one juz of the Qur’an daily, Group 2 recited half a juz daily, and Group 3 served as a control. Echocardiographic measurements of LVOT-VTI and ejection fraction (EF) were performed at baseline and after 30 days. Significant improvements in EF were observed in Groups 1 and 2 (p = 0.000), while no significant change was found in the control group (p = 0.260). LVOT-VTI increased significantly in Groups 1 and 2 (p = 0.020) but not in Group 3 (p = 0.090). LVOT-VTI is an independent prognostic marker in HFrEF, and these findings support further well-designed clinical trials to evaluate the clinical benefits of Qur’an recitation.

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Author Biographies

dr. Nurkhalis, Sp.JP-FIHA,FAsCC, Universitas Syiah Kuala, Banda Aceh

Doctorate School of Medical Science

Medical Faculty Universitas Syiah Kuala

Prof. Dr. dr. H. Kurnia Fitri Jamil, M.Kes, Sp.PD-KPTI, FINASIM, University of Syiah Kuala

Head of the division of tropical and infectious diseases of Internal Medicine

Medical Faculty Universitas Syiah Kuala

Dr.dr. Imran SpS(K), M.Kes, Universitas Syiah Kuala

Head of the division of neurology Medicine Medical Faculty Universitas Syiah Kuala

Dr.dr. Muhammad Yamin, SpJP(K), SpPD, Universitas Indonesia

Cardiology division of internal Medicine Medical Faculty University of Indonesia